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Week 16 Fantasy Football Injury Report | Patrick Mahomes, Joe Mixon, Jaylen Waddle, Zach Ertz and More

These are all the injuries you need to monitor throughout the week.

Mark Morales-Smith Dec 19th 8:12 AM EST.

Nov 28, 2024; Green Bay, Wisconsin, USA;  Miami Dolphins wide receiver Jaylen Waddle (17) is tackled by Green Bay Packers linebacker Isaiah McDuffie (58) and linebacker Quay Walker (7) during the fourth quarter at Lambeau Field. Credit: Jeff Hanisch-Imagn Images
Nov 28, 2024; Green Bay, Wisconsin, USA; Miami Dolphins wide receiver Jaylen Waddle (17) is tackled by Green Bay Packers linebacker Isaiah McDuffie (58) and linebacker Quay Walker (7) during the fourth quarter at Lambeau Field. Credit: Jeff Hanisch-Imagn Images

Quarterbacks

Patrick Mahomes, Kansas City Chiefs (Ankle)

After an injury scare in Week 15, Mahomes is now practicing in full and fully expected to suit up for Week 16. 

Geno Smith, Seattle Seahawks (Knee)

Smith is battling through a knee injury and hoping to play this weekend. However, he is far from a lock and should be monitored heading into the weekend. 

Aidan O'Connell, Las Vegas Raiders (Knee)

O'Connell is practicing in full this week and looks set to return to action in Week 16 barring a setback to a knee injury that was once believed to be season-ending. 

Running Backs

Joe Mixon, Houston Texans (Ankle)

Mixon suffered an injured ankle after again being taken down by a hip-drop tackle in Week 15. He finished the game but he did the same earlier in the season before missing multiple games. It sounds like he is trending towards playing this week, but it is worth keeping an eye on. 

David Montgomery, Detroit Lions (Knee)

Montgomery suffered what is believed to be a season-ending knee injury in Week 15. He will go for a second opinion but is expected to ultimately land on IR. 

Kenneth Walker III, Seattle Seahawks (Calf)

Walker is not practicing and is in danger of missing his third straight game. Zach Charbonnet has also popped up on the injury report, so you'll want to monitor this backfield closely. 

Bucky Irving, Tampa Bay Buccaneers (Hip/Back)

Irving fought through injuries last week and we expect him to do the same this week barring any setbacks regardless of his practice status. 

Breece Hall, New York Jets (Knee)

Hall was listed as a DNP on Wednesday, however, he is expected to play in Week 16 after returning in Week 15. 

Jaleel McLaughlin, Denver Broncos (Quad)

McLaughlin has been ruled out for Thursday Night Football in Week 15. This makes Javonte Williams and Audric Estime slightly more intriguing. 

Tony Pollard, Tennessee Titans (Ankle)

Pollard went down with an ankle injury in Week 15, opening up the door for Tajae Spears to have a big fantasy day. He should be considered very questionable for Week 16 and Spears becomes a fantasy option if Pollard can't go. 

Isaac Guerendo, San Francisco 49ers (Hamstring)

We don't know much about this injury, but hamstrings are always concerning. Should he be forced to miss any time, Patrick Taylor would be the projected lead back for San Fran. 

Nick Chubb, Cleveland Browns (Foot)

Chubb has been placed on injured reserve with a foot injury and his season is over. 

Tyrone Tracy, New York Giants (Ankle)

Tracy is dealing with an ankle injury, but doesn't look to be in any serious jeopardy of sitting out Week 16. 

Sincere McCormick, Las Vegas Raiders (Ankle)

McCormick has been placed on IR with an ankle injury and his season is over. 

Roschon Johnson, Chicago Bears (Concussion)

Johnson has returned to practice and appears to be on track to return for Week 16.

Wide Receivers

CeeDee Lamb, Dallas Cowboys (Shoulder)

Lamb will be dealing with this shoulder issue for the remainder of the season. He's in much more danger of leaving the game than sitting out this week though. 

George Pickens, Pittsburgh Steelers (Hamstring)

Pickens continues to be hampered by his injured hammy and is tracking towards missing another game this week. 

DK Metcalf, Seattle Seahawks (Shoulder)

Metcalf has been playing through his ailing shoulder and is expected to do the same this week. 

Jakobi Meyers, Las Vegas Raiders (Ankle)

Meyers played through his ankle injury in Week 15 and is on track to play again in Week 16 despite his injury designation. 

Marquise Brown, Kansas City Chiefs (Shoulder)

Brown is practicing in full and it looks like he has a real shot to make his season debut on Saturday. 

Nick Westbrook-Ikhine, Tennessee Titans (Ankle)

NWI is dealing with an ankle sprain and could end up being a game-time decision this week. 

Malik Nabers, New York Giants (Knee/Foot)

Nabers left the field limping on Sunday after being stepped on, however, he returned and played well. We don't expect him to miss any time. 

Michael Pittman, Indianapolis Colts (Back)

Pittman has been dealing with a back issue for most of the season, but his DNP to start the week is likely just to rest it. 

Jaylen Waddle, Miami Dolphins (Knee)

Waddle left with a knee injury in Week 15 and in a rare occurrence didn't return to the game despite standing on the sidelines with his helmet. His status for Week 16 is very much up in the air. 

Tight Ends

David Njoku, Cleveland Browns (Hamstring)

Njoku was forced to miss Week 15 and is very questionable for Week 16. 

Zach Ertz, Washington Commanders (Concussion)

It's unlikely Ertz will play this week after exiting with a concussion in Week 15. 

Will Dissly, Los Angeles Chargers (Shoulder)

Dissly has been ruled out for Thursday Night Football. 

#injuries

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